Detergents Interfere with Mass Spec Analysis & Other Downstream Applications!
Rapid Detergent Removal, More Mass Spec. Peaks!
Remember: Improper sample preparation results in poor data!
Detergents are essential for protein solubility during protein extraction and sample preparation, especially when working with hydrophobic proteins. The presence of high concentrations of detergents in protein samples can impair ELISA, IEF, protease digestion of proteins and suppress peptide ionization when analyzed by mass spectrometry.
Our DetergentOUT™ GBS10 resin removes free, unbound anionic, nonionic or zwitterionic detergents (e.g. SDS, Triton® X-100 or CHAPS) from aqueous protein and peptide samples with minimal sample loss for downstream analysis by mass spectrometry and other techniques.
- Remove Free Aqueous Detergents
- Prevent Interference of Downstream Applications
- Improve Mass Spec. Detection
The application note shows how DetergentOUT™ GBS10 improves mass spec detection of peptides after detergent removal.
Download the free application note to find the key to improved mass spectrometry analysis!